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The following symptoms, anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia (psychomotor restlessness), hypomania, and mania, have been reported in adult and pediatric patients being treated with antidepressants for major depressive disorder as well as for other indications, both psychiatric and nonpsychiatric

Clinical studies have shown that a 500 mg daily dose of resveratrol for 3 months can significantly reduce the VAS score, but the improvement in joint structure is limited (49)

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