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ROS reaction with DNA may lead to mutagenesis, disruption of the cell cycle, and induction of apoptosis [8,9]

10.1016/j.jalz.2012.12.001 Alzheimers Dement

Lille, Institut Pasteur de Lille, Lille, France Background: Systemic inflammation, triggered by bacteria or Pathogen-Associated Molecular Patterns (PAMPs), is a primary driver of acute-on-chronic liver failure (ACLF), a severe syndrome affecting patients with acutely decompensated cirrhosis (Hernaez et al., Gut , 2016)

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doi: 10.1016/j.bcp.2004.07.009

(2016) 55:e1416