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Subsequently, another haplotype analysis in 195 Japanese subjects sequenced all 5 exons, the promoter and enhancer regions, and all flanking introns

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NF-B is a key transcriptional regulator of inflammatory mediators and leads to, for example, increased expression of TNF-, IL-6, IL-8, E-selectin, VCAM-1, and ICAM-1 [166,167,168]

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