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Patients need to team up with their healthcare team to safely manage these interactions

Appendix Table S4, and (van Eckert et al, 2006))

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And the numbers from clinical trials comparing these two compounds tell a story that is impossible to ignore

A need for markedly increased amounts of opioids to achieve intoxication or desired effect

This is worth noting if tirzepatide-related insomnia is already disrupting your sleep, as heartburn can make sleep quality even worse