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B vitamins are water soluble vitamins and it is flushed through the body quickly and cannot be stored, and must be fed to the dog with each meal according to Wendy Volhard in the Holistic Guide for the Healthy Dog

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Regulation of AdoMet-to-AdoHcy levels by vitamin B 12 could be an important mechanism by which it can influence cholesterol biosynthesis pathway in human adipocytes

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