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These interconnected pathwaysinvolving iron metabolism (TRIM7, COPZ1, IRP-IRE), antioxidant defenses (NF-B, Nrf2, APOC1), and lipid peroxidation regulation (ACSL4, PRRX2/GCH1/BH4)collectively determine ferroptosis susceptibility in GBM

Health care institutions, clinicians and general population must be aware of the importance of nutrition, as source of natural antioxidants, in our physical and mental state, as much in health as in illness

[3] These studies also suggest that DSIP could attenuate the excitatory actions of NMDA receptors, further contributing to its sleep-promoting properties

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