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Cancer Res (2009) 69(20):798693

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MORE Immediately following the first and only uses of the atomic bomb in Hiroshima and Nagasaki, President Truman described nuclear stewardship as an awful responsibility that has fallen to us.i The decision to use the bombs did clearly demonstrate the operational effectiveness of a new and awesome weapon, as the atomic

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To test this hypothesis, we stably knocked down the expression of LRRC8A, the mandatory subunit of VRAC channels 10 , in THP-1 cells by using a lentiviral-based shRNA strategy, silencing LRRC8A expression by more than 80% as compared with parental control cells (Fig