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Lancet 380 , 21972223 (2012)

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This characteristic has allowed researchers to study its systemic biological effects across multiple experimental models

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The vaccine, which does not use mRNA technology but instead contains a recombinant version of a specific viral protein, as well as an adjuvant to boost immune protection, is approved under emergency use authorization

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Read our full breakdown of the July 2026 review

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Other models use a co-culture of astrocytes, pericytes, neural stem cells and human induced pluripotent stem cell-derived BBB endothelial cells to improve BBB integrity [116]

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