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Merrill JT, June J, Koumpouras F et al (2018) Top-line results of a phase 2, double-blind, randomized, placebo-controlled study of a reversible B cell inhibitor, XmAb5871, in systemic lupus erythematosus (SLE)

[18] [19] Their detoxification involves both broad-spectrum and specialized enzymatic systems, including families that act on reactive carbonyls and other electrophiles, as well as dedicated pathways for particularly toxic intermediates

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All types of subjects were included and divided into different groups including healthy subjects, obese subjects and others, to clarify the cross-effect between IF and subjects under different physiological and pathophysiological situations, including pregnancy, perioperative periodendocrine disease, cancer and autoimmune diseases

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