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Apatinib was approved by the China Food and Drug Administration (CF-DA) in 2014 for the treatment of third-line and above-advanced GC (124), making it a new option for patients with GC who failed in second-line treatment (125)

Unlike cyanocobalamin, hydroxocobalamin offers sustained release, ensuring longer-lasting benefits for those with B12 deficiency, fatigue, or general wellness concerns

(2016) BPC-157 restores intestinal barrier function in sepsis models Lee et al

Statistical analysis for two-group comparisons was conducted using unpaired Student's t-test

We recommend future research directions to determine when to start with SL, IM, or oral vitamin B12 in different situations