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But reduced production tells only half the story

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Other genes, such as GPAT1 , GPAT2, APAT4 , CPT2, ACC1 , ACSL1 , ACSL4 , FATP1 , FATP3 , FATP4 , and FATP6 , were not significantly altered

Plant Physiol Biochem 47:10821088 AOAC (2000) Official methods of analysis

Moreover, the disease exhibits a female preponderance with an overall female-to-male ratio of 4:1 (1, 2, 21)

Because the concentration of PQ in the brain following acute exposure is low, the possibility of neurotoxicity by PQ was overlooked in earlier studies as it was thought that the blood-brain barrier (BBB) would impede PQ entry into the brain