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If you can't find the local guidelines online, best bet is probably to submit a FOI (Freedom of Information) request to your ICB/Health board asking which B12 deficiency guidelines they are using and for a link to or copy of them

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For patients in the Miami area who are not candidates for GLP-1 medications, or who have already used them and want to address the body composition residue that appetite suppression alone does not fix, tesamorelin fills a gap those medications leave

Another approach to modulate NNMT involves bisubstrate inhibitors, which are designed to resemble both the substrate (NAM) and the cofactor (SAM)