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For those without an absorption problem, research suggests that high-dose oral B12 supplements can be as effective as injections in raising and maintaining B12 levels

For injectable routes, such as subcutaneous, research models might start with doses around 0.5mg to 2mg daily for an equivalent 70kg subject

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NICE guidance (CG189: Obesity: identification, assessment and management) recommends that all patients undergoing bariatric surgery receive comprehensive pre- and post-operative nutritional support

Advantages of Oral B12 Supplements Oral supplements have several advantages: Convenience: Easy to take at home without clinic visits Non-invasive: No needles or injections required Cost-effective: Generally less expensive than injections Variety: Multiple formulations allow personal preference and flexibility Suitable for mild deficiencies or preventive supplementation For many people without absorption problems, oral B12 supplements are sufficient to maintain healthy levels

Under these conditions, the peptide maintains structural integrity for extended periods