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Our single-cell analysis revealed that sarcoid skin granulomas specifically induced TLS-forming signaling pathways, including CXCL12/CXCR4 signaling

In the following principles for attachement of biologically active molecules to multimerisation domains are described, but same principles may be applied to attachment of adjuvant molecules, immune target molecules or any other molecules to multimerisation domains

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In addition, gene mutations in these degradation enzymes can falsify the result

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