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The N and Ctermini of each enzyme are adjacent (Figures 1B and 4D, E) supporting the view that the circular permutations are reversible at the genetic level

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Urinary iodine concentrations for determining iodine status deficiency in populations

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It is important to note that AE1plays an important role in the maintenance of the structural integrity of erythrocytes, providing interactions between the membrane and the cytoskeleton, supporting the cytoskeletal connectivity, and maintaining the biconcave shape of erythrocytes [92]

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[link] M.J. Hooshmand, B.J. Cummings, and A.J. Anderson. , "Improved pre-embedded immuno-electron microscopy procedures to preserve myelin integrity in mammalian central nervous tissue. ", In: Microscopy: advances in scientific research and education (2014)

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