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The process of oxidative stress leads to pigmentation so the treatment aims to decrease this stress

doi: 10.3109/03602532.2016.1157600 153 WeiskirchenRTackeF

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The reduction of roGFP2 WT (S 2 ) required both PfGrx and GSH (Fig

Lastly, ferroptosis can trigger systemic inflammatory response, activate multiple pro-inflammatory signaling, induce cardiomyocyte hypertrophy, fibrosis and death, and eventually lead to chronic adverse ventricular remodeling (Shirazi et al., 2017