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Experimental Material Gold (III) chloride trihydrate (HAuCl 4 3H 2 O, 99.9% trace metals basis) was obtained from Solarbio (China)

Clinical review: oxygen as a signaling molecule

However, melatonins receptors can be Gq-coupled and activate phospholipase C (PLC), which hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2), producing inositol triphosphate (IP3) and 1,2-diacylglycerol (DAG), which increases Ca +2 levels and activates calmodulin (CaM) and CaM kinase signaling [158, 159]

Serum ALT and proinflammatory cytokines were measured by ELISA

Polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs), which are pathologically activated neutrophils, undergo a transition from their normal state under the influence of ferroptosis (Kim 2022)