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Conservative titration (6 to 8 week holds) For people who are GI-sensitive, have a history of poor tolerance to GLP-1 medications, or simply prefer to minimize side effects at the cost of slower initial results

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While all of these compounds stimulate natural growth hormone release, they differ in their side effects, duration of action, and interaction with other hormones like ghrelin , cortisol , and prolactin

J Biol Chem 276: 1916019165, 2001

The safety ratings for both peptides focus on side effects in the digestive tract, such as sickness, vomiting, and diarrhea