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An interaction with the dopamine system has already been noted for many known peptides (neurotensin, CCK, etc.)

Furthermore, inflammation in the gut has been linked to an increase in circulating pro-inflammatory cytokines, which are known to contribute to kidney damage and fibrosis (Lau et al., 2015)

Tirzepatide adds GIP receptor activation, pushing results higher

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These immune cells are made inside bone marrow and travel through the body inside lymph vessels, which are in close contact with the bloodstream

After screening titles and abstracts, publications lacking sufficient relevance to the topic, publications in pre-print format, and publications in languages other than English were excluded