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In such scenarios, directional selection is more effectively reflected by a diminished level of genetic variation, rather than the traditional Hardy-Weinberg equilibrium (HWE) expectations [65]

International Journal of Medical Sciences, 12(1), 10-25

Increased VEGF increased ocular permeability and neovascularization and accelerated the development of diabetic retinopathy [110]

Upregulation of HO-1 with cobalt metalloporphyrin protoporphyrin IX (CoPP) in hRSV-infected mice significantly reduced disease-related body weight loss and induced an upregulation of IFN-/ in the lungs, indicating that HO-1 plays an important role in the development of the antiviral type I IFN response in the airways (106)