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Additionally, plasmatic Gln measurement in the patients showed that those with lower levels presented a worse outcome (mortality, LOS, and infections) in which a supplementation with higher doses might be necessary

Statements Ethics statement All mouse experiments were performed in strict accordance with all provisions of the Animal Welfare Act, the Guide for the Care and Use of Laboratory Animals, and the PHS Policy on Humane Care and Use of Laboratory Animals

Thus, mice lacking CSE have reduced levels of sulfydration and lower GAPDH activity

Neurological damage: Promote neuroprotection and helps in recovery from neurological impairments

Reactive oxygen species and the central nervous system

Finally, in BTC, cisplatin-gemcitabine remains the standard first-line therapy, with mOS ranging from 12.6 to 13.5 months and mPFS of 5.57.4 months (NCT02182778) [30]