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Abstract As the population ages, Parkinsons disease (PD) has become a prevalent neurodegenerative disorder, posing a significant threat to the health and quality of life of the elderly

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Antioxidants can counteract oxidative stress and mitigate all the effects on human health

Indeed, recently there have been several studies reporting an impact of acquired 5FU resistance on mitochondrial biology

The main antioxidant enzymes involved in converting hazardous wastes into nontoxic or biodegradable materials include catalases, superoxide dismutases, xanthine oxidases, and glutathione peroxidases

Moreover, in contrast to asthma and COPD, where enhanced SubP and/or tachykinin signaling is potentially pathogenic, a decrease in SubP-mediated secretion in CF might be of detriment [99]