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10.1093/annonc/mds142 186 KochA.JeilerB.RoedigJ.van WijkS

Targets skin and connective tissue regeneration

The Wnt/-catenin signaling pathway is another critical driver of GC development and metastasis

Discussion Recently, a novel bifunctional enzyme GshF has aroused concerns about GSH productive capacity as most reported GshFs are insensitive to feedback inhibition of GSH except that of P

Due to the increased glutamate concentration in the protruding gap, NMDAR on astrocytes cannot drive the intracellular mechanism to exert a neuroprotective effect, resulting in a reduction in the supply of antioxidant glutathione induced by this mechanism, which further strengthens the toxic effect of glutamic acid (52)