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High expression of GT is commonly found on cells involved in transport, on the luminal surface of secretory and absorptive cells

Fibroblast cultures are commonly used to measure transcriptional responses involving matrix-associated proteins, growth signaling regulators, and stress-response pathways

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for example, the GPX4 gene becomes methylated following treatment of nucleus pulposus cells by HCys, resulting in lower levels of both GPX4 mRNA and protein [79]