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The reaction mixture contained 25 mM phosphate buffer (pH 7.0), 0.05% guaiacol, 1.0 mM H 2 O 2 and 100 l enzyme extract

Some people notice improved energy or less tingling within days, but meaningful relief of numbness or burning from neuropathy can take several weeks to months

Compared to their noncovalent analogues, these covalent PROTACs exhibit equal or greater target degradation efficacy due to more favorable PK properties [224]

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