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Description

Thus, purine catabolism appears to be a homeostatic response of mitochondria to oxidant stress and may protect against progressive mitochondrial dysfunction in certain disease states (Kristal et al., 1999)

Golgi and ER proteins used in Fig

These seem to be for local use, perhaps more shorter term storage days/months

Thus, measurement of GR activity is used as indicator for oxidative stress

Reactive oxygen species (ROS) deposition is a significant driver of, IE as well as one of its effects, which can cause oxidative stress in the erythroid cells