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35 36 Cytochrome P450 2E1 CYP2E1 oxidizes ethanol, 37 with CYP1A2 and CYP3A4 contributing to lesser extents

cerana cerana, the expression of AccGSTS1 was high when exposed to various environmental stressors such as temperature (cold and heat shock), heavy metal (HgCl 2 ), pesticides (phoxim, cyhalothrin, and acaricide), H 2 O 2 , and ultraviolet [45] radiation which are known for their property to generate oxidative stress [55]

doi: 10.1089/ars.2012.5136 100 PusztahelyiT

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In humans, regulation occurs largely at the level of enzyme expression and activity in response to nutrient availability and stress