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Acknowledgements We thank the core facilities of the Flow Cytometry Core, Metabolomics Core, and the Laboratory of Animal Research at the Convergence Medicine Research Center (CREDIT), Asan Medical Center, for the use of their shared equipment, services, and expertize

The number of follicles, including primordial follicles, was estimated using the physical dissector stereological method based on the entire ovary

Unlike growth hormone secretagogues or other peptide compounds, 5-amino-1-MQ works by blocking the NNMT enzyme, which methylates nicotinamide (a form of vitamin B3) and reduces the availability of NAD+ (nicotinamide adenine dinucleotide) in cells

In the UK, some patients are supported to self-inject at home, but only after proper training and with medical oversight

TB-500 Thymosin Beta-4 (Tb4), the full 43-amino-acid peptide - the research name TB-500 refers to this peptide