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Both peptides ship lyophilized and are reconstituted before use, most commonly with bacteriostatic water, and both should be stored cold and protected from repeated freeze-thaw cycles

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Notably, the full spectrum of clinical features associated with B12 deficiency is much broader, is nonspecific, and may occur as a consequence of other diseases

This is due to biotin sharing its transporter with vitamin B5, so theoretically taking high doses of one could impair uptake of the other

Joo Carlos Locatelli, Juliene Gonalves Costa, Haynes A, Naylor LH, P