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Exploiting CRISPR/Cas9-mediated excision, the successful rescue of phenotypes in DRGs derived from gene-edited FRDA patient iPSCs has been reported

"Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression." Molecular Psychiatry, 5(6), 616-632.

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Mol Cell Endocrinol 461:205214 Wang Y, Zhang Z, Guo W, Sun W, Miao X, Wu H et al (2014) Sulforaphane reduction of testicular apoptotic cell death in diabetic mice is associated with the upregulation of Nrf2 expression and function

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