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5.7 Artificial intelligence (AI) in diagnosis and monitoring AI and machine learning (ML) are revolutionizing PD management through: Early diagnosis : analyzing digital biomarkers (e.g., voice, gait, handwriting)

Changes in glutamate metabolism may damage excitotoxic neurons [16]

Moreover, abdominal pain, anorexia, and headaches may occur and, more rarely, gallstones, pancreatitis, and severe allergic reactions are observed [25]

Sulfhydryl groups are also present in antioxidant enzymes, such as glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), and catalase, which explains why mercury toxicity often leads to oxidative stress [44, 45], mitochondrial dysfunction [46], and apoptosis [47]

They can play the role of GLP-1

The chemical composition of the nanoparticles also determines their pH, which influences the permeability of the BBB