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SELENOS has a role in the removal of stressor-induced misfolded proteins from the ER, preventing the accumulation of these proteins and the subsequent stress response that leads to activation of NF-B, pro-inflammatory cytokine gene transcription and the inflammation cascade (Fig

Enzyme-responsive biomimetic ferritin nanoparticles (MMFn) engineered with MMP-2/9-responsive peptides demonstrated robust antitumor activity in Panc02 pancreatic cancer xenograft models without systemic toxicity (122)

DUSP10 (MKP5) DUSP10 (also named as MAPK phosphatase 5, MKP5) dephosphorylates JNK and p38 in vitro [186] and in African green monkey COS-7 kidney fibroblasts [187]

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Moreover, pyocyanin inhibits bacterial pathogenesis by hindering biofilm formation which is necessary for bacterial survival and resistance