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methods of obtaining antigens having greater tolerogenicity and/or have improved antigenicity), antigens which have improved antigenicity, genetic vaccine-mediated tolerance, and modulation of the immune response by inclusion of appropriate accessory molecules

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Therefore, the specific negative implications of this alteration remain open for in-depth discussion

doi: 10.3168/jds.2015-10040 78 OgilvieLSpricigoJFMionBVan WintersBKarrowNAMcBrideBWet al