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Treatment of patients with small-molecule antioxidants or antioxidant enzymes did not yield the desired benefits (Lirussi et al

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While tightly regulated MLCK and ROCK signalling supports normal epithelial transport and barrier modulation, excessive or sustained activation of these pathways contributes to pathological intestinal barrier dysfunction observed in inflammatory and infectious conditions (Xiong et al., 2026)

Screening of missing proteins in the human liver proteome by improved MRM-approach-based targeted proteomics

Incell NMR spectroscopy further reveals that a range of WTL mutants (A4V, I35T, G37R, G93A, I113T) exist predominantly as unstructured apoproteins unable to bind zinc when overexpressed in human HEK293T cells, or when expressed and purified from E