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Hence, ApoE deficient mice have been used widely to study mechanisms of atherosclerotic lesion development

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However, more intensive studies are needed to gain a better understanding of the mechanisms of action ( The present study aimed to assess the potential therapeutic effects of PA on APAP-induced hepatotoxicity and the possible underlying mechanisms through its effects on CYP2E1 gene expression, serum and tissue iron load, oxidative stress and SIRT-1 expression

Several studies have investigated the potential of fungal and plant-derived enzymes to degrade ochratoxin A (OTA) efficiently, highlighting their application in sustainable detoxification approaches