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Akram [email protected] This article was submitted to Plant Physiology, a section of the journal Frontiers in Plant Science Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Currently, research is focused on the development of highly selective inhibitors targeting specific HDAC subtypes, particularly HDAC6, which retain immunomodulatory activity while substantially reducing toxicity [243, 244]

Studies also indicate that when theres a high presence of extracellular NAD + , P2RX7 receptors can facilitate cell death of the gut TRM cells (172)

5 However, although peroxide treatment initially reduced PHD activity, prolonged exposure enhanced it

[PubMed] 130: Busik JV, Olson LK, Grant MB, Henry DN