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Recent findings indicate that excessive ROS production in HT leads to structural changes in thyroglobulin and thyroid peroxidase, increasing their immunogenicity (Batg et al

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Finally, as intracellular GSH synthesis partially contributed to tGSH levels in the TIF, we explored the impact of blocking GSH export through drug transporters 37

6.1.3 Biopsy and histopathology: definitive diagnosis While imaging techniques elucidate important information on the diseases presence and its extent, examination of tissue via a histopathological approach remains the definitive diagnosis method