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Additionally, atrazine, benalaxyl, bromacil, butachlor, butylene fipronil, fenamiphos, fipronil, fomesafen, pretilachlor and simazine were tested in a screening study of sorption ability of CD:EPI, CD:EPI, HPCD:EPI, randomly methylated CD:EPI (RM-CD:EPI), equimolar mixture of --CD:EPI, HPCD:EPI and HPCD:EPI and a physical mixture of CD:EPI, HPCD:EPI and RM-CD:EPI with mass ratio of 40:30:30 (w/w) (multiplex)

In one crucial area called lipid metabolism, 34 genes (or 14% of the total) were upregulated by up to 41-fold and 19 genes (or 8% of the total) were downregulated by up to 3-fold

However, in agreement with a causal role of moderately elevated circulating homocysteine levels in cardiovascular disease, some putative mechanisms have been identified that may explain the atherothrombogenicity of hyperhomo- cysteinemia