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While theres no definite cutoff for when B12 starts to become unsafe, because people often ask, well somewhat arbitrarily say not to take more than 1,000 g per day over the long-term without guidance from a physician

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Among participants with prediabetes at baseline, 87.7% achieved normoglycemia, highlighting the potential of this combination therapy to modify the natural history of dysglycemia

Oncology clearance and individualized risk assessment are essential