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Diseases associated with glutathione depletion include neurodegenerative disorders (Alzheimers, Parkinsons, Huntingtons diseases, amyotrophic lateral sclerosis, Friedreichs ataxia), pulmonary disease (COPD, asthma, and acute respiratory distress syndrome), immune diseases (HIV, autoimmune disease), cardiovascular diseases (hypertension, myocardial infarction, cholesterol oxidation), chronic age-related diseases (cataracts, macular degeneration, hearing impairment, and glaucoma), liver disease, cystic fibrosis and the aging process itself

Cells were collected and then incubated with serum-free DMEM containing 10 M DCFH-DA for 30 min at 37

Redox active or thiol reactive

Molecular mechanisms that link oxidative stress, inflammation, and fibrosis in the liver

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10.1016/j.jdiacomp.2012.04.004 133 HosseiniB.SaedisomeoliaA.Allman-FarinelliM