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Skeletal muscle protein balance regulation Skeletal muscle mass depends on the rates of protein synthesis and degradation

In: Litwack G (ed) Human biochemistry

Given that inhibition of IGF-IR may paradoxically lead to upregulation of IGF1/2 expression, and IGF1/2 have IGF-IR/InsR-independent functions, it warrants to investigate whether co-targeting IGF and IGF-IR/InsR-A may achieve objective responses

Given the predicted reductase activity of Rha1 and Rha2 and their structural similarity to proteins that metabolize enone-containing compounds, we further investigated their role in 4-HNE resistance

AMPK is a dominant negative regulator of mTORC1

10.1016/j.plaphy.2013.10.012 53 SchippersJ