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Utilizing feline oral squamous cell carcinoma patients to develop NQO1-targeted therapy

The absence of SCD1 in T cells results in the hydrolysis of triglycerides and phosphatidylcholine by adipose triglyceride lipase

The work presented here, published in the journal Biomedicine s, builds a bridge between laboratory bench and bedside by showing proof-of-concept that supplementing people with HIV specifically with a combination of glycine and N-acetylcysteine, which we call GlyNAC, as precursors of glutathione, a major antioxidant produced by the body, improves multiple deficits associated with premature aging, said Sekhar

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revealed that OXPHOS phenotypes determine metabolic dependencies and therapeutic outcomes in NSCLC, suggesting a direct link between mitochondrial bioenergetics and cancer progression (Han et al

Frequent inactivation of cysteine dioxygenase type 1 contributes to survival of breast cancer cells and resistance to anthracyclines