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Interrupting glycolysis is highly valued as a therapeutic strategy, because glycolytic disruption is generally tolerated in mammals

Domestic Anim Endocrinol 23(12):3342 Niisato N, Marunaka Y (2023) Therapeutic potential of multifunctional myricetin for treatment of type 2 diabetes mellitus

GSH is found predominantly in the cytosol (~90%), with smaller but vital pools in mitochondria and the endoplasmic reticulum

Importantly, glutathione (GSH) acts as an essential cofactor for the enzyme family glutathione peroxidases (GPx), which catalyze the reduction of hydrogen peroxide and lipid hydroperoxides into water and their corresponding alcohols

But people should be cautious about taking supplements in general, particularly glutathione

When patients lose their balance, their feet and hands cannot move quickly enough to break a fall