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Description

It binds to actin and promotes cell migration including the mobilisation, migration, and differentiation of stem/progenitor cells that form new blood vessels and regenerate tissue

Detergents were used at the following concentrations: 1% (w/v) DDM plus 0.1% (w/v) CHS, 1% (w/v) DDM, 1% (w/v) lauryl maltose neopentyl glycol (MNG), 1% (w/v) MNG plus 0.1% (w/v) CHS, 1% digitonin, and 1% (w/v) glyco-diosgenin (GDN)

Phase I studies from the late 1980s using IGF-1 to treat Larons Syndrome (GH insensitivity) revealed effective increase in linear growth reaching adult heights using doses ranging from 80 to 240 g/kg/day [264268]