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Copper is a required cofactor for enzymes involved in connective-tissue crosslinking, angiogenesis, and antioxidant defense, and GHK appears to function partly as a copper-delivery vehicle that makes the metal bioavailable to cells in a controlled way

Bone, Connective Tissue, and Vascular Effects GHK-Cu promotes bone healing, enhances osteoblastic cell attachment, and increases collagen synthesis in bone cells

(a) Gastrointestinal trials (Ulcerative Colitis) A Croatian research group conducted: A phase I safety study in healthy men A phase II trial of a rectal BPC-157 formulation for mildmoderate ulcerative colitis These are only available as abstracts and drug summaries , not as full peer-reviewed publications with methods, statistics, or adverse event profiles

10.1007/s00701-019-03868-7 16 DrmicD.KolencD.IlicS.BaukL.SeverM.Zenko SeverA.et al (2017)

People undergoing microneedling, laser, or resurfacing treatments : Copper peptides enhance post-procedure recovery and support healing