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17,18 Off-Label Uses of Ketamine Ketamine originally was designed to be used as an anesthetic, but clinicians frequently use ketamine for off-label indications, including depression, status epilepticus, headache, and pain

PMID: 96 MardanyanSKarapetyanLAntonyanA

PMID: 36592824

10.1038/leu.2013.54 Leukemia 64 GarnierN.RedstoneG

The discussion considers several potential mechanisms for DSIPs observed benefits suggesting DSIP could be associated with the rescuing of neurons in motor cortex and subcortical structures involved in motor control

For example, LAT1-targeted nanocarriers bind to the LAT1 and lock the transporter in an occluded conformation, which results in the inhibition of cellular LAT1-mediated amino acid uptake