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Tanaka N et al

In hAD-MSCS, chromatin immunoprecipitation (ChIP) analysis revealed Argonaute 2 directly regulated OCT4, which targeted Methyl-CpG Binding Domain Protein 6 (MBD6) to regulate genes associated with stemness-associated genes and self-renewal activity of MSCs [24] (Fig

Addressing these areas will not only deepen the understanding of ferroptosis in DN but also facilitate the development of precise, translatable therapeutic strategies for this globally prevalent cause of ESRD