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The need to find new agents for refractory patients has led to the development of mAb-based therapies

This overlap makes B12 deficiency easy to miss during GLP-1 therapy, because both the patient and the prescriber attribute these symptoms to the medication itself rather than investigating a correctable nutritional deficit

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In the SURMOUNT-1 trial, people treated with tirzepatide lost up to 22.5% of their body weight over 72 weeks , making it even more effective than semaglutide (NEJM tirzepatide study)

However, the guide will have emergency communication at all times