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The protocol first involved collating various kinetic values from literature, and assigning each value a weight to represent their plausibility, based on the organism, enzyme and conditions under which the kinetic parameter was measured

Endocrine 48(3):756775

Environ Sci Technol 35:36763682 Magellan K, Barral-Fraga L, Rovira M, Srean P, Urrea G, Garca-Berthou E, Guasch H (2014) Behavioural and physical effects of arsenic exposure in fish are aggravated by aquatic algae

n = 6 each)

Mild adverse events, including conjunctivitis and upper respiratory tract infections, occurred but resolved promptly (62, 63)

All three inhibitors bind primarily to the hydrophobic or electrophile binding site (H-site) 5 of GSTO1, but do so in unique ways (Supplementary Fig