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These inflammatory factors further elicit inflammatory responses in retinal cells by activating downstream signaling pathways, including NF-B and janus kinase (JAK)/signal transducer and activator of transcription (STAT), resulting in cellular damage and apoptosis (Figure 5)

, 11 , 239, doi: Shibata, Y., Yasui, H., Higashikawa, K., Miyamoto, N., and Kuge, Y

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